Chemistry
IUPAC Name: Sodium
Synonyms of Sodium hydride (CAS NO.7646-69-7): EINECS 231-587-3 ; HSDB 745 ; NAH 80 ; Sodium hydride (NaH) ; Sodium monohydride ; Sodium hydride [UN1427] [Dangerous when wet] ; UN1427
CAS NO: 7646-69-7
Molecular Formula: HNa
Molecular Weight: 24
Molecular Structure:
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Melting Point: 800 °C
ProductCategories: Inorganics ; Classes of Metal Compounds ; Na (Sodium) Compounds (excluding simple sodium salts) ; Reduction ; Synthetic Organic Chemistry ; Typical Metal Compounds ; Materials for Hydrogen Storage ; Metal Hydrides ; Metal HydridesAlternative Energy ; Synthetic Reagents
Density: 1.2 g/cm3
Flash Point: 185°C
Storage temp.: Store at RT.
Form powder: (moistened with oil)
Water Solubility: REACTS
Sensitive: Air & Moisture Sensitive
Merck: 14,8625
Uses
Sodium hydride (CAS NO.7646-69-7) is primarily used as a strong base in the organic synthesis.It is a base of wide scope and utility in the organic chemistry. It has the main uses as follows:
1.capable of deprotonating a range of even weak Bronsted acids to give the corresponding sodium derivatives. The resulting sodium derivatives can be alkylated.
2.Sodium hydride is most notably employed to deprotonate carbon acids such as 1,3-dicarbonyls and analogues such as malonic esters.
3.It is widely used to promote condensation reactions of carbonyl compounds via the Dieckmann condensation, Stobbe condensation, Darzens condensation, and Claisen condensation.
4.Sodium hydride is also used to make sulfur ylides, which in turn are used to convert ketones into epoxides.Sodium hydride reduces certain main group compounds, but the analogous reactivity is unknown in the organic chemistry.
5.Because of its rapid and irreversible reaction with water, Sodium hydride can be used to dry some organic solvents.
Toxicity Data With Reference
| 1. | ipr-rat LD50:91 mg/kg | IJEBA6 Indian Journal of Experimental Biology. 5 (1967),96. | ||
| 2. | scu-rat LD50:279 mg/kg | IJEBA6 Indian Journal of Experimental Biology. 5 (1967),96. | ||
| 3. | ivn-rat LD50:105 mg/kg | IJEBA6 Indian Journal of Experimental Biology. 5 (1967),96. | ||
| 4. | ipr-mus LD50:83 mg/kg | IJEBA6 Indian Journal of Experimental Biology. 5 (1967),96. | ||
| 5. | scu-mus LD50:400 mg/kg | 85GDA2 CRC Handbook of Antibiotic Compounds, Volumes 1-9. 8 (1)(1982),331. | ||
| 6. | ivn-mus LD50:97 mg/kg | IJEBA6 Indian Journal of Experimental Biology. 5 (1967),96. |
Safety Profile
Hazard Codes of Sodium hydride (CAS NO.7646-69-7): 
F
Risk Statements: 15-36
R15: Contact with water liberates extremely flammable gases.
R36: Irritating to eyes.
Safety Statements: 26-43-7/8-24/25
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S43: In case of fire use ... (there follows the type of fire-fighting equipment to be used.)
S7: Keep container tightly closed.
S8: Keep container dry.
S24/25: Avoid contact with skin and eyes.
RIDADR: UN 1427 4.3/PG 1
WGK Germany: 3
RTECS: WB3910000
F: 10-21
HazardClass: 4.3
PackingGroup: I
Specification
Sodium hydride (CAS NO.7646-69-7) can ignite in air, especially upon contacting with water to release hydrogen.